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Basophils; An increased percentage of basophils may be due to: after splenectomy, allergic reaction, chronic myelogenous leukemia, collagen vascular disease, myeloproliferative disease, or varicella infection. A decreased percentage of basophils may be due to: acute infection, cancer, or severe injury.
**It is important to realize that an abnormal increase in one type of white blood cell can cause a decrease in the percentage of other types of white blood cells.
Eosinophils; An increased percentage of eosinophils may be due to: Addison disease, allergic reaction, cancer, chronic myelogenous leukemia, collagen vascular disease, hypereosinophilic syndromes, or parasitic infection.
**It is important to realize that an abnormal increase in one type of white blood cell can cause a decrease in the percentage of other types of white blood cells.
Hematocrit; measures the percentage of a person’s total blood volume that consists of red blood cells.
Hemoglobin; is an iron-rich protein in red blood cells that carries oxygen. The blood test measures the total amount of this oxygen-carrying protein in the blood, which generally reflects the number of red blood cells in the blood.
Immature Granulocytes; With the exception of blood from neonates or pregnant women, the appearance of immature granulocytes in the peripheral blood indicates an early-stage response to infection, inflammation or other stimuli of the bone marrow. Being able to detect them quickly and reliably opens doors to new diagnostic possibilities for related disorders. Current areas of research regarding the diagnostic significance of circulating immature granulocytes focus on the early and rapid discrimination of bacterial from viral infections, particularly in children, recognizing bacterial infection in neonates, and the early recognition of bacterial infection and sepsis in adults, which is of vital importance in particular for intensive care patients.
Lymphocytes; Lymphocytes are a part of the white blood cells. They are made up of ‘T’ cells which remove foreign objects that are not supposed to be in the body and ‘B’ cells which are instrumental in the immune system. They produce antibodies when a suspicious foreign object is found in the blood. The other type of lymphocyte is the natural killer cell. They simply kill any object found in the cell that is considered to be abnormal such as tumor cells or infections. Lymphocytes are associated with infections and diseases. An elevation in the level of lymphocytes is considered to be a sign of a viral infection. An increased percentage of lymphocytes may be due to: chronic bacterial infection, infectious hepatitis, infectious mononucleosis, lymphocytic leukemia, multiple myeloma, viral infection (such as mumps or measles) A decreased percentage of lymphocytes may be due to: chemotherapy, leukemia, radiation therapy or exposure, sepsis, steroid use and HIV which is a cause for extremely low levels of ‘T’ cells.
**It is important to realize that an abnormal increase in one type of white blood cell can cause a decrease in the percentage of other types of white blood cells.
MCH; (Mean corpuscular hemoglobin) is a calculation of the average amount of hemoglobin inside a single red blood cell.
MCHC; (Mean corpuscular hemoglobin concentration) is a calculation of the average concentration of hemoglobin inside a single red blood cell.
MCV; (Mean corpuscular volume) is a measurement of the average size of a single red blood cell.
Monocytes; Measures the number or percentage of monocytes, which are white blood cells that move out of the circulating blood and into the tissues, where they mature into macrophages. An increased percentage of monocytes may be due to: chronic inflammatory disease, leukemia, parasitic infection, tuberculosis, viral infection (for example, infectious mononucleosis, mumps, or measles.
**It is important to realize that an abnormal increase in one type of white blood cell can cause a decrease in the percentage of other types of white blood cells.
Neutrophil; Measures the number or percentage of neutrophils, which are normally the most abundant circulating white blood cells and respond quickly to infection. Any infection or acute stress increases your number of white blood cells. High white blood cell counts may be due to inflammation, an immune response, or blood diseases such as leukemia. An increased percentage of neutrophils may be due to: acute infection, acute stress, eclampsia, gout, myelocytic leukemia, rheumatoid arthritis, rheumatic fever, thyroiditis, or trauma. A decreased percentage of neutrophils may be due to: aplastic anemia, chemotherapy, influenza (flu), radiation therapy or exposure, viral infection, or widespread severe bacterial infection.
**It is important to realize that an abnormal increase in one type of white blood cell can cause a decrease in the percentage of other types of white blood cells.
Platelets; A platelet count that’s lower than normal (thrombocytopenia) or higher than normal (thrombocytosis) is often a sign of an underlying medical condition, or it may be a side effect from medication. If your platelet count is outside the normal range, you’ll likely need additional tests to diagnose the cause.
RBC; A red blood cell count that’s higher than normal (erythrocytosis), or high hemoglobin or hematocrit levels, could point to an underlying medical condition, such as polycythemia vera or heart disease.
RDW; Red cell distribution width is a parameter that measures variation in red blood cell size or red blood cell volume. RDW is elevated in accordance with variation in red cell size (anisocytosis), ie, when elevated RDW is reported on complete blood count, marked anisocytosis (increased variation in red cell size) is expected on peripheral blood smear review.
WBC; A low white blood cell count (leukopenia) may be caused by a medical condition, such as an autoimmune disorder that destroys white blood cells, bone marrow problems or cancer. Certain medications also can cause white blood cell counts to drop. If your white blood cell count is higher than normal, you may have an infection or inflammation. Or, it could indicate that you have an immune system disorder or a bone marrow disease. A high white blood cell count can also be a reaction to medication.
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